En 2006, elle partage la vedette avec Meryl Streep dans la comédie Le Diable s'habille en Prada, qui rencontre un énorme succès commercial dès sa sortie en salles.En 2008, sa prestation dans Rachel se marie lui vaut de remporter de nombreux prix, recevant une nomination à l'Oscar de la meilleure actrice.Jake: I do honestly believe that Annie would have changed her body however it needed to be changed for the character. Jake: When we decided that this was going to be a love story - because I think at first it was a script about a guy who changes as a result of meeting a girl - and when Annie came onto the project it changed, and it became about two people falling in love.If Parkinson's meds made you gain weight or something happened to you somehow, you know, you became Ironman or something, she would have done that, I mean, she really would have, that's the kind of actress she is. And I think we understood that if we were going to tell a love story, you know, one of the essential elements of a love story is sex, and it should be.
But when we meet in a Manhattan hotel close to her home, she looks vulnerable and girlish.
magazine, 10 years after the premiere of Brokeback Mountain.
In a special feature, the cast and crew look back on the making of the film, exploring the cultural impact and significance surrounding it then and now."Heath had decided that at some point Ennis had been in an accident and had a limp.
En 2012, elle incarne Selina Kyle dans The Dark Knight Rises et Fantine dans Les Misérables.
Sa prestation dans Les Misérables lui a valu d'obtenir des critiques élogieuses et plusieurs récompenses, dont le Golden Globe, le SAG Award, le BAFTA Award et l'Oscar de la meilleure actrice dans un second rôle.